Falkenberg CV, Azeloglu EU, Stothers M, Deerinck TJ, Chen Y, He JC, Ellisman MH, Hone JC, Iyengar R, Loew LM.
Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability.
PLoS Comput Biol. 2017 Mar 16;13(3):e1005433.
PMID: 28301477 |
PMCID:
PMC5373631
|
EndNote Citation Hu M, Azeloglu EU, Ron A, Tran-Ba KH, Calizo RC, Tavassoly I, Bhattacharya S, Jayaraman G, Chen Y, Rabinovich V, Iyengar R, Hone JC, He JC,4, Kaufman LJ.
A biomimetic gelatin-based platform elicits a pro-differentiation effect on podocytes through mechanotransduction.
Sci Rep. 2017 Mar 6;7:43934.
PMID: 28262745 |
PMCID:
PMC5338254
|
EndNote Citation Stillitano F, Hansen J, Kong CW, Karakikes I, Funck-Brentano C, Geng L, Scott S, Reynier S, Wu M, Valogne Y, Desseaux C, Salem JE, Jeziorowska D, Zahr N, Li R, Iyengar R, Hajjar RJ, Hulot JS.
Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells.
Elife. 2017 Jan 30;6.
PMID: 28134617 |
PMCID:
PMC5279943
|
EndNote Citation Bouhaddou M, Birtwistle MR.
Kinetic Models of Biochemical Signaling Networks
Systems Pharmacology and Pharmacodynamics, Chapter 6 (02 December 2016)
PaperMarc R. Birtwistle, Jens Hansen, James M. Gallo, Sreeharish, Muppirisetty, Peter Man-Un Ung, Ravi Iyengar, Avner Schlessinger
Systems Pharmacology: An Overview
Systems Pharmacology and Pharmacodynamics, Chapter 4 (02 December 2016)
PaperBouhaddou M, DiStefano MS, Riesel EA, Carrasco E, Holzapfel HY, Jones DC, Smith GR, Stern AD, Somani SS, Thompson TV, Birtwistle MR.
Drug response consistency in CCLE and CGP.
Nature. 2016 Nov 30;540(7631):E9-E10.
PMID: 27905419
|
EndNote Citation Song RS, Tolentino R, Sobie EA, Neves-Zaph SR.
Cross-regulation of Phosphodiesterase 1 and Phosphodiesterase 2 Activities Controls Dopamine-mediated Striatal α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Trafficking.
J Biol Chem. 2016 Oct 28;291(44):23257-23267.
PMID: 27605670 |
PMCID:
PMC5087742
|
EndNote Citation Devenyi RA, Ortega FA, Groenendaal W, Krogh-Madsen T, Christini DJ2, Sobie EA.
Differential roles of two delayed rectifier potassium currents in regulation of ventricular action potential duration and arrhythmia susceptibility.
J Physiol. 2016 Oct 24. doi: 10.1113/JP273191
PMID: 27779762
|
EndNote Citation Mayourian J, Savizky RM, Sobie EA, Costa KD
Modeling Electrophysiological Coupling and Fusion between Human Mesenchymal Stem Cells and Cardiomyocytes.
PLoS Comput Biol. 2016 Jul 25;12(7):e1005014.
PMID: 27454812 |
PMCID:
PMC4959759
|
EndNote Citation Lancaster MC, Sobie EA.
Improved Prediction of Drug-Induced Torsades de Pointes Through Simulations of Dynamics and Machine Learning Algorithms.
Clin Pharmacol Ther. 2016 Oct;100(4):371-9
PMID: 26950176
|
EndNote Citation Krogh-Madsen T, Sobie EA, Christini DJ.
Improving cardiomyocyte model fidelity and utility via dynamic electrophysiology protocols and optimization algorithms.
J Physiol. 2016 May 1;594(9):2525-36. doi: 10.1113/JP270618
PMID: 26661516 |
PMCID:PMC4850194
|
EndNote Citation Devenyi RA, Sobie EA.
There and back again: Iterating between population-based modeling and experiments reveals surprising regulation of calcium transients in rat cardiac myocytes.
J Mol Cell Cardiol. 2016 Jul;96:38-48.
PMID: 26235057 |
PMCID:PMC4733425
|
EndNote Citation Gallo, JM, Birtwistle MR.
Network pharmacodynamic models for customized cancer therapy.
Wiley Interdiscip Rev Syst Biol Med. 2015 Jul;7(4):243-51.
PMID: 25914386
|
EndNote Citation Azeloglu EU, Iyengar R.
Good practices for building dynamical models in systems biology.
Sci Signal. 2015 Apr 7;8(371).
PMID: 25852187
|
EndNote Citation Poláková E, Illaste A, Niggli E, Sobie EA.
Maximal acceleration of Ca2+ release refractoriness by β-adrenergic stimulation requires dual activation of kinases PKA and CaMKII in mouse ventricular myocytes.
J Physiol. 2015 Mar 15;593(6):1495-507
PMID: 25772298
|
EndNote Citation Birtwistle MR.
Analytical reduction of combinatorial complexity arising from multiple protein modification sites.
J R Soc Interface. 2015 Feb 6;12(103).
PMID: 25519995
|
EndNote Citation Clark NR, Hu KS, Feldmann AS, Kou Y, Chen EY, Duan Q, Ma'ayan A.
The Characteristic Direction: A Geometrical Approach to Identify Differentially Expressed Genes.
BMC Bioinformatics 2014 Mar 21;15:79.
PMID: 24650281 |
PMCID:
PMC4000056
|
EndNote Citation Azeloglu EU, Hardy SV, Eungdamrong NJ, Chen Y, Jayaraman G, Chuang PY, Fang W, Xiong H, Neves SR, Jain MR, Li H, Ma'ayan A, Gordon RE, He JC, Iyengar R.
Interconnected network motifs control podocyte morphology and kidney function.
Sci Signal. 2014 Feb 4;7(311):ra12
PMID: 24497609 |
EndNote Citation Zhang XY, Birtwistle MR, Gallo JM.
A general network pharmacodynamic model-based design pipeline for customized cancer therapy applied to the VEGFR pathway.
CPT Pharmacometrics Syst Pharmacol. 2014 Jan 15;3:e92.
PMID: 24429593 |
EndNote Citation Lee P, Sobie EA, Peskin CS.
Computer simulation of voltage sensitive calcium ion channels in a dendritic spine.
J Theor Biol. 2013 Dec 7;338:87-93.
PMID: 23999286 |
EndNote Citation Isaacson SA, Larabell CA, Le Gros MA, McQueen DM, Peskin CS.
The influence of spatial variation in chromatin density determined by x-ray tomograms on the time to find DNA binding sites.
Bull Math Biol. 2013 Nov;75(11):2093-117.
PMID: 23955281 |
EndNote Citation Zhao S, Nishimura T, Chen Y, Azeloglu EU, Gottesman O, Giannarelli C, Zafar MU, Benard L, Badimon JJ, Hajjar RJ, Goldfarb J, Iyengar R.
Systems pharmacology of adverse event mitigation by drug combinations.
Sci Transl Med. 2013 Oct 9;5(206):206ra140
PMID: 24107779 |
Supplementary Materials |
EndNote Citation Song RS, Massenburg B, Wenderski W, Jayaraman V, Thompson L, Neves SR.
ERK regulation of phosphodiesterase 4 enhances dopamine-stimulated AMPA receptor membrane insertion.
Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15437-42
PMID: 23986500 |
EndNote Citation Rangamani P, Lipshtat A, Azeloglu EU, Calizo RC, Hu M, Ghassemi S, Hone J, Scarlata S, Neves SR, Iyengar R.
Decoding Information in Cell Shape
Cell. 2013 Sep 12154(6):1356-69
Article |
PMID: 24034255 |
EndNote Citation Xu H, Baroukh C, Dannenfelser R, Chen EY, Tan CM, Kou Y, Kim YE, Lemischka IR, Ma'ayan A.
ESCAPE: database for integrating high-content published data collected from human and mouse embryonic stem cells.
Database (Oxford). 2013 Jun 21;2013:bat045.
PMID: 23794736 |
PMCID: PMC3689438 |
EndNote Citation Tan CM, Chen EY, Dannenfelser R, Clark NR, Ma'ayan A.
Network2Canvas: network visualization on a canvas with enrichment analysis.
Bioinformatics. 2013 Aug 1;29(15):1872-8.
PMID: 23749960
|
PMCID: PMC3712222 |
EndNote Citation Zhong Y, Chen EY, Liu R, Chuang PY, Mallipattu SK, Tan CM, Clark NR, Deng Y, Klotman PE, Ma'ayan A, He JC.
Renoprotective Effect of Combined Inhibition of Angiotensin-Converting Enzyme and Histone Deacetylase.
J Am Soc Nephrol. 2013 Apr;24(5):801-11.
PMID: 23559582 |
PMCID: PMC3636790
|
EndNote Citation Lee YS, Liu OZ, Hwang HS, Knollmann BC, Sobie EA.
Parameter sensitivity analysis of stochastic models provides insights into cardiac calcium sparks.
Biophys J. 2013 Mar 5;104(5):1142-50.
PMID: 23473497 |
EndNote CitationHansen J, Iyengar R.
Computation as the Mechanistic Bridge Between Precision Medicine and Systems Therapeutics
Clin Pharmacol Ther. 2013 Jan;93(1):117-28.
PMID: 23212109 |
EndNote Citation Ma'ayan A.
Colliding Dynamical Complex Network Models: Biological Attractors versus Attractors from Material Physics.
Biophys J. 2012 Nov 7;103(9):1816-7
PMID: 23199907|
PMCID: PMC3491669 |
EndNote Citation Gautier EL, Shay T, Miller J, Greter M, Jakubzick C, Ivanov S, Helft J, Chow A, Elpek KG, Gordonov S, Mazloom AR, Ma'ayan A, Chua WJ, Hansen TH, Turley SJ, Merad M, Randolph GJ; the Immunological Genome Consortium.
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages.
Nat Immunol. 2012 Sep 30. doi: 10.1038/ni.2419
PMID: 23023392
|
PMCID: PMC3558276 |
EndNote Citation Zhou Q, Lv H, Mazloom AR, Xu H, Ma'ayan A, Gallo JM
Activation of Alternate Pro-Survival Pathways Accounts for Acquired Sunitinib Resistance in U87MG Glioma Xenografts.
J Pharmacol Exp Ther. 2012 Aug 6
PMID: 22869928 |
PMCID: PMC3477209 |
Abstract
Stinchcombe A, Peskin CS, Tranchina D.
Population density approach for discrete mRNA distributions in generalized switching models for stochastic gene expression.
Physical Review. E, Statistical, nonlinear, and soft matter physics 85, 061919 (2012)
Abstract |
EndNote Citation Kou Y, Betancur C, Xu H, Buxbaum JD, Ma'ayan A.
Network-and attribute-based classifiers can prioritize genes and pathways for autism spectrum disorders and intellectual disability.
Am J Med Genet C Semin Med Genet. 2012 May 15;160C(2):130-42.
PMID: 22499558 |
PMCID: PMC3505691 |
EndNote Citation Jin Y, Ratnam K, Chuang PY, Fan Y, Zhong Y, Dai Y, Mazloom AR, Chen EY, D'Agati V, Xiong H, Ross MJ, Chen N, Ma'ayan A, He JC.
A systems approach identifies HIPK2 as a key regulator of kidney fibrosis.
Nat Med. 2012 Mar 11;18(4):580-8.
PMID: 22406746 |
EndNote Citation |
ArticleHwangpo TA, Jordan D, Premsrirut PK, Jayamaran G, Licht J, Iyengar R, Neves SR.
GRIN modulates Sprouty repression of MAPK activation by growth factor stimulation.
J Biol Chem. 2012 Mar 1.
PMID: 22383529 |
EndNote Citation
Zhao S, Iyengar R.
Systems pharmacology: network analysis to identify multiscale mechanisms of drug action.
Annu Rev Pharmacol Toxicol. 2012 Feb 10;52:505-21.
PMID: 22235860 |
EndNote Citation
Wenderski WC, Neves SR.
Modeling of spatial intracellular signaling events in neurons.
Methods Enzymol. 2012;505:105-24
PMID: 22289450
Rozenfeld R, Bushlin I, Gomes I, Tzavaras N, Gupta A, Neves S, Battini L, Gusella GL, Lachmann A, Ma'ayan A, Blitzer RD, Devi LA.
Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons.
PLoS One. 2012;7(1):e29239.
PMID: 22235275 |
PMCID: PMC3250422 |
EndNote Citation
Ding J, Xu H, Faiola F, Ma'ayan A, Wang J
Oct4 links multiple epigenetic pathways to the pluripotency network.
Cell Res. 2012 Jan;22(1):155-67.
PMID: 22083510 |
PMCID: PMC3252465 |
EndNote Citation
Chen EY, Xu H, Gordonov S, Lim MP, Perkins MH, Ma'ayan A
Expression2Kinases: mRNA Profiling Linked to Multiple Upstream Regulatory Layers.
Bioinformatics. 2012 Jan 1;28(1):105-11.
PMID: 22080467 |
PMCID: PMC3244772 |
EndNote Citation
Liu OZ, Lederer WJ, Sobie EA.
Does the Goldilocks Principle apply to calcium release restitution in heart cells?
J Mol Cell Cardiol. 2012 Jan;52(1):3-6.
PMID: 22056316 |
EndNote Citation
Mazloom AR, Dannenfelser R, Clark NR, Grigoryan AV, Linder KM, Cardozo TJ, Bond JC, Boran ADW, Iyengar R, Malovannaya A, Lanz RB, Ma'ayan A
Recovering Protein-Protein and Domain-Domain Interactions from Aggregation of IP-MS Proteomics of Coregulator Complexes.
PLoS Comput Biol. 7(12): e1002319.
PMID: 22219718 |
PMCID: PMC3248428 |
EndNote Citation
Abul-Husn NS, Annangudi SP, Ma'ayan A, Ramos-Ortolaza DL, Stockton SD Jr, Gomes I, Sweedler JV, Devi LA
Chronic morphine alters the presynaptic protein profile: identification of novel molecular targets using proteomics and network analysis.
PLoS One. 2011;6(10):e25535.
PMID: 22043286 |
PMCID: PMC3197197 |
EndNote Citation
Baroukh C, Jenkins SL, Danenfelser R, Ma'ayan A.
Genes2WordCloud: a quick way to identify biological themes from gene lists and free text.
Source Code Biol Med. 2011 Oct 13;6(1):15.
PMID: 21995939 |
PMCID: PMC3213042 |
EndNote Citation
Sobie EA, Lee YS, Jenkins SL, Iyengar R.
Systems biology--biomedical modeling.
Sci Signal. 2011 Sep 13;4(190):tr2
PMID: 21917716 |
PMCID: PMC3188945 |
EndNote Citation
Miller LK, Devi LA.
The highs and lows of cannabinoid receptor expression in disease: mechanisms and their therapeutic implications.
Pharmacol Rev. 2011 Sep;63(3):461-70.
PMID: 21752875 |
PMCID: PMC3141881 |
EndNote Citation
Ramay HR, Liu OZ, Sobie EA.
Recovery of cardiac calcium release is controlled by sarcoplasmic reticulum refilling and ryanodine receptor sensitivity.
Cardiovasc Res. 2011 Sep 1;91(4):598-605.
PMID: 21613275 |
PMCID: PMC3156908 |
EndNote Citation
Sobie EA, Sarkar AX.
Regression methods for parameter sensitivity analysis: applications to cardiac arrhythmia mechanisms.
Conf Proc IEEE Eng Med Biol Soc. 2011;2011:4657-60.
PMID: 22255376 |
EndNote Citation
Jia Z, Valiunas V, Lu Z, Bien H, Liu H, Wang HZ, Rosati B, Brink PR, Cohen IS, Entcheva E.
Stimulating Cardiac Muscle by Light: Cardiac Optogenetics by Cell Delivery.
Circ Arrhythm Electrophysiol. 2011 Aug 9.
PMID: 21828312 |
PMCID: PMCID: PMC3209525 |
EndNote Citation
Neves SR.
Modeling of spatially-restricted intracellular signaling.
Wiley Interdiscip Rev Syst Biol Med. 2011 Jul 15.
PMID: 21766466 |
EndNote Citation
Liu J, Fackelmayer OJ, Hicks DB, Preiss L, Meier T, Sobie EA, Krulwich TA.
Mutations in a Helix-1 Motif of the ATP Synthase c-Subunit of Bacillus pseudofirmus OF4 Cause Functional Deficits and Changes in the c-Ring Stability and Mobility on Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis.
Biochemistry. 2011 Jun 21;50(24):5497-506.
PMID: 21568349 |
PMCID: PMC3115392 |
EndNote Citation
Sarkar AX, Sobie EA.
Quantification of repolarization reserve to understand interpatient variability in the response to proarrhythmic drugs: A computational analysis. Heart Rhythm. 2011 Jun 7.
PMID: 21699863 |
EndNote Citation
Bhalla US.
Multiscale interactions between chemical and electric signaling in LTP induction, LTP reversal and dendritic excitability.
Neural Netw. 2011 May 10.
PMID: 21616637 |
EndNote Citation
Rozenfeld R, Gupta A, Gagnidze K, Lim MP, Gomes I, Lee-Ramos D, Nieto N, Devi LA.
AT1R-CB1R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II.
EMBO J. 2011 May 3;30(12):2350-63.
PMID: 21540834 |
PMCID: PMC3116274 |
EndNote Citation
Leigh SY, Tattu A, Mitchell JS, Entcheva E.
M3: Microscope-based maskless micropatterning with dry film photoresist.
Biomed Microdevices. 2011 Apr;13(2):375-81.
PMID: 21190086 |
EndNote Citation
Golebiewska U, Johnston JM, Devi L, Filizola M, Scarlata S.
Differential response to morphine of the oligomeric state of μ-opioid in the presence of δ-opioid receptors.
Biochemistry. 2011 Apr 12;50(14):2829-37.
PMID: 21361347 |
PMCID: PMC3048119 |
EndNote Citation
Guo Y, Golebiewska U, Scarlata S.
Modulation of Ca2+ activity in cardiomyocytes through caveolae-Gαq interactions.
Biophys J. 2011 Apr 6;100(7):1599-607.
PMID: 21463572 |
PMCID: PMC3072606 |
EndNote Citation
Isaacson SA, McQueen DM, Peskin CS.
The influence of volume exclusion by chromatin on the time required to find specific DNA binding sites by diffusion.
Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3815-20.
PMID: 21300894 |
PMCID: PMC3048119 |
EndNote Citation
Chung CY, Bien H, Sobie EA, Dasari V, McKinnon D, Rosati B, Entcheva E.
Hypertrophic phenotype in cardiac cell assemblies solely by structural cues and ensuing self-organization.
FASEB J. 2011 Mar;25(3):851-62.
PMID: 21084696 |
PMCID: PMC3042840 |
EndNote Citation
Rangamani P, Fardin MA, Xiong Y, Lipshtat A, Rossier O, Sheetz MP, Iyengar R.
Signaling network triggers and membrane physical properties control the actin cytoskeleton-driven isotropic phase of cell spreading.
Biophys J. 2011 Feb 16;100(4):845-57.
PMID: 21320428 |
PMCID: PMC3037558 |
EndNote Citation
Gomes I, Dale CS, Casten K, Geigner MA, Gozzo FC, Ferro ES, Heimann AS, Devi LA.
Hemoglobin-derived peptides as novel type of bioactive signaling molecules.
AAPS J. 2010 Dec;12(4):658-69.
PMID: 20811967 |
PMCID: PMC2976993 |
EndNote Citation
Xu H, Schaniel C, Lemischka IR, Ma'ayan A.
Towards a complete in-silico, multi-layered embryonic stem cell regulatory network.
Wiley Interdiscip Rev Syst Biol Med. 2010 Nov-Dec;2(6):708-33.
PMID: 20890967 |
PMCID: PMC2951283 |
EndNote Citation
Lachmann A, Xu H, Krishnan J, Berger SI, Mazloom AR, Ma'ayan A.
ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments. Bioinformatics. 2010 Oct 1;26(19):2438-44.
PMID: 20709693 |
PMCID: PMC2944209 |
EndNote Citation
Cecchi GA, Rao AR, Xiao Y, Kaplan E.
Statistics of natural scenes and cortical color processing.
J Vis. 2010 Sep 1;10(11):21.
PMID: 20884516 |
EndNote Citation Babadi B, Casti A, Xiao Y, Kaplan E, Paninski L.
A generalized linear model of the impact of direct and indirect inputs to the lateral geniculate nucleus.
J Vis. 2010 Aug 24;10(10):22.
PMID: 20884487 |
EndNote Citation Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, Mizuno K, Ma'ayan A, Gygi SP, Lefkowitz RJ.
Global phosphorylation analysis of {beta}-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15299-304.
PMID: 20686112 |
PMCID: PMC2930550 |
EndNote Citation
Méndez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma'ayan A, Enikolopov GN, Frenette PS.
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche.
Nature. 2010 Aug 12;466(7308):829-34.
PMID: 20703299 |
PMCID: PMC3146551 |
EndNote Citation
Gupta A, Mulder J, Gomes I, Rozenfeld R, Bushlin I, Ong E, Lim M, Maillet E, Junek M, Cahill CM, Harkany T, Devi LA.
Increased abundance of opioid receptor heteromers after chronic morphine administration.
Sci Signal. 2010 Jul 20;3(131):ra54.
PMID: 20647592 |
PMCID: PMC3125674 |
EndNote Citation
Sobie EA, Jenkins SL, Iyengar R, Krulwich TA. 2010.
Training in systems pharmacology: Pre-doctoral program in pharmacology and systems biology at Mount Sinai School of Medicine.
Clin Pharmacol Ther. 2010 Jul;88(1):19-22.
PMID: 20562890 |
PMCID: PMC3037798 |
EndNote Citation
Lee P, Griffith BE, Peskin CS.
The immersed boundary method for advection-electrodiffusion with implicit timestepping and local mesh refinement.
J Comput Phys. 2010 Jul 1;229(13):5208-5227.
PMID: 20454540 |
PMCID: PMC2864960 Xiong Y, Rangamani P, Fardin MA, Lipshtat A, Dubin-Thaler B, Rossier O, Sheetz MP, Iyengar R.
Mechanisms controlling cell size and shape during isotropic cell-spreading.
Biophys J. 2010 May 19;98(10):2136-46.
PMID: 20483321 |
PMCID:PMC2872297 |
EndNote CitationHardy S and Iyengar R. 2010.
Analysis of dynamical models of signaling networks with Petri nets and dynamic graphs.
Modeling in Systems Biology, Computational Biology, 2011, Volume 16, Part 3, 225-251.
Krulwich TA, Liu J, Morino M, Fujisawa M, Ito M, Hicks DB. 2010.
Adaptive mechanisms of extreme alkaliphiles. Extremophiles Handbook.
Horikoshi K, Antranikian G, Bull AT, Robb FT, Stetter KO. (Eds.).
Yamada YR, Peskin CS.
The influence of look-ahead on the error rate of transcription.
Math. Mod. Nat. Phen. 2010 Apr; 5(3): 206-227.
PMID: 22162915 |
PMCID: PMC3235181
Golebiewska U, Scarlata S.
The effect of membrane domains on the G protein-phospholipase Cbeta signaling pathway.
Crit Rev Biochem Mol Biol. 2010 Apr;45(2):97-105.
PMID: 20128735 |
PMCID: PMC2857923
Lipshtat A, Jayaraman G, He JC, Iyengar R.
Design of versatile biochemical switches that respond to amplitude, duration, and spatial cues. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1247-52.
PMID: 20080566 |
PMCID: PMC2824311 |
EndNote Citation
Zorina Y, Iyengar R, Bromberg KD.
Cannabinoid 1 receptor and interleukin-6 receptor together induce integration of protein kinase and transcription factor signaling to trigger neurite outgrowth.
J Biol Chem. 2010 Jan 8;285(2):1358-70.
PMID: 19861414 |
PMCID: PMC2801262 |
EndNote Citation
Isaacson SA, Isaacson D.
Reaction-diffusion master equation, diffusion-limited reactions, and singular potentials.
Rev E Stat Nonlin Soft Matter Phys. 2009 Dec;80(6 Pt 2):066106.
PMID:20365230 |
EndNote Citation
Lu R, Markowetz F, Unwin RD, Leek JT, Airoldi EM, MacArthur BD, Lachmann A, Rozov R, Ma'ayan A, Boyer LA, Troyanskaya OG, Whetton AD, Lemischka IR.
Systems-level dynamic analyses of fate change in murine embryonic stem cells.
Nature. 2009 Nov 19;462(7271):358-62.
PMID:19924215 |
EndNote Citation
Cordeddu V, Di Schiavi E, Pennacchio LA, Ma'ayan A, Sarkozy A, Fodale V, Cecchetti S, Cardinale A, Martin J, Schackwitz W, Lipzen A, Zampino G, Mazzanti L, Digilio MC, Martinelli S, Flex E, Lepri F, Bartholdi D, Kutsche K, Ferrero GB, Anichini C, Selicorni A, Rossi C, Tenconi R, Zenker M, Merlo D, Dallapiccola B, Iyengar R, Bazzicalupo P, Gelb BD, Tartaglia M.
Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair. Nat Genet. 2009 Sep;41(9):1022-6.
PMID: 19684605 |
PMCID: PMC2765465 |
EndNote Citation
Gomes I, Grushko JS, Golebiewska U, Hoogendoorn S, Gupta A, Heimann AS, Ferro ES, Scarlata S, Fricker LD, Devi LA.
Novel endogenous peptide agonists of cannabinoid receptors.
FASEB J. 2009 Sep;23(9):3020-9.
PMID: 19380512 |
PMCID: PMC2735371 |
EndNote Citation
Protas L, Dun W, Jia Z, Lu J, Bucchi A, Kumari S, Chen M, Cohen IS, Rosen MR, Entcheva E, Robinson RB.
Expression of skeletal but not cardiac Na+ channel isoform preserves normal conduction in a depolarized cardiac syncytium. Cardiovasc Res. 2009 Feb 15;81(3):528-35.
PMID: 18977767 |
PMCID:PMC2639131 |
EndNote Citation
Xiao Y. and Kaplan E. 2009. Information about color and orientation in the primate visual cortex In: High Throughput Image Analysis and Reconstruction/A. R. Rao and G. Cecchi, (Eds.) Artech House Publishing, Ch. 10:219-229.
Ma'ayan A, Cecchi GA, Wagner J, Rao AR, Iyengar R, Stolovitzky G.
Ordered cyclic motifs contribute to dynamic stability in biological and engineered networks. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19235-40.
PMID: 19033453 |
PMCID: PMC2614745 |
EndNote CitationNeves SR, Tsokas P, Sarkar A, Grace EA, Rangamani P, Taubenfeld SM, Alberini CM, Schaff JC, Blitzer RD, Moraru II, Iyengar R.
Cell shape and negative links in regulatory motifs together control spatial information flow in signaling networks. Cell 2008;133(4):666-80.
PMID: 18485874 |
PMCID: PMC2728678 |
EndNote CitationRoyer CA, Scarlata SF.
Fluorescence approaches to quantifying biomolecular interactions. Methods Enzymol. 2008;450:79-106.
PMID: 19152857 |
EndNote Citation
Last Updated: