GATE
GATE is a software system used to analyze time-series expression data. It creates cluster files from time-series data for visualization as movies. It uses prior knowledge interaction networks and gene-lists libraries for identification of biological themes identified using the clustering analysis.
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URL: http://amp.pharm.mssm.edu/maayan-lab/gate.htm
Lists2Networks
Lists2Networks is a web-based software system used to analyze lists of mammalian genes. It creates a similarity matrix for many uploaded lists and compares the resultant lists to libraries of gene-lists from different categories. Users can create networks of lists and expand lists with prior knowledge networks such as protein-protein interactions, co-expression or co-annotation networks.
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URL: http://www.lists2networks.org
Presynaptome: Network of protein-protein interactions within the synapse
Literature-based protein-protein interactions extracted from low-throughput experimental studies reporting interactions in mammalian presynaptic nerve terminals.
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URL: http://amp.pharm.mssm.edu/presynaptome/
Neuronal Signalome
Literature-based cell signaling interactions extracted from literature describing components and interactions in mammalian neurons. This dataset was used in the paper (Ma'ayan et al. published in Science Aug. 12 2005).
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Adhesome
Literature-based protein-protein interaction network extracted from publications describing functional interactions in adhesion complexes of mammalian cells.
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iScMid
Literature-based protein-protein and gene-regulatory interactions extracted from publication describing interactions in mouse and human embryonic stem cells.
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URL: http://amp.pharm.mssm.edu/iscmid
KEA
Kinase-substrate interactions collected from several databases collecting literature-based kinase-substrate interactions from experimental studies of mammalian cells.
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URL: http://amp.pharm.mssm.edu/lib/kea.jsp
Genes2Networks
Protein-protein interactions collected from several databases collecting literature-based protein-protein interactions from experimental studies of mammalian cells.
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URL: http://actin.pharm.mssm.edu/genes2networks
PathwayGenerator
Automatically generated pathways from receptors to effectors created using the neuronal signalome.
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Files for download: A collection of Sig Files, and OWL Files (BioPAX2, BioPAX3) created from the Neuronal Signalome.
URL: http://amp.pharm.mssm.edu/maayan-lab/pg/
Cycles Study
Six biological directed networks of different types and three man-made directed networks of different types used to the analysis of large directed cycles.
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URL: http://www.pnas.org/content/105/49/19235/suppl/DCSupplemental
Neuro2A differentiation by Galphai/o pathway on Science Signaling
Cell signaling pathways that traces downstream signaling pathways from Gi/o-coupled GPCRs to key protein kinases and key transcription factors involved in neuronal differentiation. Components in the Science Signaling Connections Map are linked to Nature Molecule Pages.
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URL: http://stke.sciencemag.org/cgi/content/abstract/2/54/cm1
DOQCS
A repository of models of signaling pathways. It includes reaction schemes, concentrations, rate constants, as well as annotations on the models. The database provides a range of search, navigation, and comparison functions.
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Membrane Diffusion Coefficients
Partial Listing of diffusion coeffficients of integral membrane proteins provided by Suzanne Scarlata, Ph.D., SBCNY Investigator.
Files for download: Membrane Diffusion Coefficients TableURL: membrane_diffusion_coefficients.htm
